#Question id: 2968
#Unit 2. Cellular Organization
What is the name of the microtubule-organizing center found in animal cells as an identifiable structure present during all phases of the cell cycle?
#Question id: 2969
#Unit 2. Cellular Organization
In the cells of many eukaryotic species, the nuclear envelope has to disappear to permit which of the following events in the cell cycle?
#Question id: 2970
#Unit 2. Cellular Organization
Describe how Cdc14 triggers the exit from mitosis in the budding yeast, S. cerevisiae.
#Question id: 2971
#Unit 2. Cellular Organization
Which one of the following is the most appropriate match?
|
Events |
Protein |
Phases |
|
A. Cohesins are loaded onto chromosomes |
I. Mei-S332/Shugoshin |
a. G1 |
|
B. Cohesins can dissociate from the DNA |
II. Polo kinase and Aurora B kinase |
b. G2 |
|
C. Prevents cohesin phosphorylation, and hence dissociation |
III. Scc2-Scc4 |
c. S |
|
D. Phosphorylation of cohesins |
IV. Pds5-Wapl |
d. M |
#Question id: 2972
#Unit 2. Cellular Organization
Match the following attachment (Column I) with definition(Column II).
|
Column I |
Column II |
|
A. Monotelic Attachment |
I. When sister kinetochores attach to microtubules emanating from opposite spindle poles, they are stably attached. |
|
B. Syntelic Attachment |
II. When one kinetochore attaches to microtubules emanating from two opposite spindle poles. |
|
C. Amphitelic Attachment |
III. When both sister kinetochores attach to microtubules emanating from the same spindle pole. |
|
D. Merotelic Attachment |
IV. When only one of the two sister kinetochores attaches to microtubules. |
Which of the following is correct?
#Question id: 2973
#Unit 2. Cellular Organization
Following statements are regarding to the spindle position checkpoint pathway in budding yeast.
A. During interphase and early mitosis, Cdc14 is sequestered and inactivated in the nucleolus. Inactive Tem1-GDP associates with the spindle pole body (SPB) nearest to the bud as soon as the mitotic spindle forms.
B. If chromosome segregation occurs properly, extension of the spindle microtubules inserts the daughter SPB into the bud, causing Tem1 to be activated by an unknown mechanism.
C. Tem1-GDP activates a protein kinase cascade, which then promotes the release of active Cdc14 from the nucleolus and exit from mitosis.
D. If the spindle apparatus fails to place the daughter SPB in the bud, Kin4 (cyan), an inhibitor of Tem1, is recruited from the parent cell cortex to the parent-cell-located SPB and maintains Tem1 in the GTP-bound form, and mitotic exit does not occur.
Which of the following are correct?