TLS Online TPP Program

#Question id: 11334


To qualify as a biodiversity hotspot, a region must meet following two strict criteria

#Unit 10. Ecological Principles
  1. Region has at least 1,500 vascular plants as endemics and must have 30% or less of its original natural vegetation
  2. Region has at least 1,500 mammal species as endemics and must have 30% or less of its original natural vegetation
  3. Region has at least 1,500 vascular plants as endemics and must have 50% of its original natural vegetation
  4. Region has at least some threatened plant species and must have 30% or less of its original natural vegetation
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TLS Online TPP Program

#Question id: 3820

#Unit 3. Fundamental Processes

Meselson and Stahlʹs experiments involved growing E. coli on a medium containing 15N (heavy nitrogen) which increased the density of the bacterial DNA. Cells were then grown on a medium containing only 14N. DNA samples were obtained for analysis after one, two and three rounds of replication (generations) and centrifuged on a density gradient. The double-helical DNA forms bands in the gradient depending on its density. How many bands did Meselson and Stahl see after two generation of cells were grown on the 14N medium?

TLS Online TPP Program

#Question id: 4558

#Unit 3. Fundamental Processes

Classes of RNA transcribed by the three eukaryotic nuclear RNA Polymerase;

                    Polymerase

             RNA Transcribed     

A. RNA polymerase I                   

i) tRNAs, 5S rRNA, snRNA, U6, 7S RNA

B. RNA polymerase II

ii) Pre-rRNA 28S, 18SrRNA,  5.8SrRNAs

C. RNA polymerase III

iii) mRNA, snRNAs, siRNAs, miRNAs

 Match the following correct combination given above combinations;

TLS Online TPP Program

#Question id: 2906

#Unit 2. Cellular Organization

A closer look at the interactions between the histones and the nucleosomal DNA reveals the structural basis for the binding and bending of the DNA within the nucleosome. Fourteen distinct sites of contact are observed, one for each time the minor groove of the DNA faces the histone octamer. State whether the following set of statements is true/false regarding this association?

I. The majority of these associations are between the proteins and the oxygen atoms in the phosphodiester backbone near the minor groove of the DNA.

II. The association of DNA with the nucleosome is mediated by a large number (about 40) of hydrogen bonds between the histones and the DNA.

III. Maximum numbers of hydrogen bonds are made between the protein side chains and the bases, and all of these are made in the minor groove of the DNA.

IV. The highly basic nature of the histones further facilitates DNA bending by masking the negative charge of the phosphates that ordinarily resists DNA bending.

V. The positively charged nature of the histones facilitates the close juxtaposition of the two adjacent DNA helices necessary to wrap the DNA more than once around the histone octamer.

TLS Online TPP Program

#Question id: 1187

#Unit 4. Cell Communication and Cell Signaling

Which protein stabilizes an intermediate in the Ras GTP hydrolysis reactions?

TLS Online TPP Program

#Question id: 11544

#Unit 7. System Physiology – Animal

When a steroid hormone and a polypeptide hormone exert similar effects on a population of target cells, then ________.