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TLS Online TPP Program

#Question id: 11477

How could you genetically modify an animal so that it would distinguish more shades of green?

#Unit 7. System Physiology – Animal
  1. Induce genes to produce a greater number of cone cells in the fovea.
  2. Introduce genes for different opsins that respond in the green region of the spectrum.

  3. Introduce genes to produce green fluid in the eyeball, because green fluids will not absorb green light.

  4. Induce increased production of cGMP to increase opening of cGMP-gated sodium channels.
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TLS Online TPP Program

#Question id: 4261

#Unit 3. Fundamental Processes

Polyadenylation can promote translation

a. of the fragile-X gene.                     

b. of stored oocyte mRNAs.

c. by allowing for greater interaction at the 5´ end.

d. by allowing for greater interaction with translation initiation factors.
TLS Online TPP Program

#Question id: 5358

#Unit 8. Inheritance Biology

In the following pedigree, individuals with shaded show presence of a recessive autosomal trait. If all individual is coming from outside the family is homozygous for normal. The calculated risk of occurrence of this trait for (?) individual is 
TLS Online TPP Program

#Question id: 7590

#General Aptitude

The ratio of the length of two trains X and Y is 4 : 7 and the ratio of the time taken by both trains to cross a man standing on a platform is 2 : 3. If the speed of the train y m/sec
TLS Online TPP Program

#Question id: 11791

#Unit 1. Molecules and their Interaction Relevant to Biology

Cellulose act as hydrophobic molecule due to
TLS Online TPP Program

#Question id: 13054

#Unit 13. Methods in Biology

Precision will be reduced, but yield will be increased
Optimisation of a PCR reaction is often a compromise between the competing demands for precision, efficiency and yield. Although the specific effects may vary, generally, increasing the annealing temperature will increase non-specific primer binding and reduce precision. Increasing the length of the elongation phase will reduce the proportion of incomplete newly-synthesised strands and therefore increase yield. In this case, the potential effect on efficiency is unclear. Increasing the elongation phase would increase the reaction time, but the time taken to ramp down to a lower annealing temperature would be reduced.
What would the expected effect be on a PCR reaction if the primers used were slightly shorter and more variable than the intended oligonucleotide sequences?