TLS Online TPP Program

#Question id: 11553


Tadpoles must undergo a major metamorphosis to become frogs. This change includes reabsorption of the tail, growth of limbs, calcification of the skeleton, increase in rhodopsin in the eye, development of lungs, change in hemoglobin structure, and reformation of the gut from the long gut of an herbivore to the short gut of a carnivore. Amazingly, all of these changes are induced by thyroxine. What is the most likely explanation for such a wide array of effects of thyroxine?

#Unit 7. System Physiology – Animal
  1. There are many different forms of thyroxine, each specific to a different tissue.
  2. Different tissues have thyroxine receptors that activate different signal transduction pathways.
  3. Some tissues have membrane receptors for thyroxine, while other tissues have thyroxine receptors within the nucleus.
  4. Different releasing hormones release thyroxine to different tissues.
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TLS Online TPP Program

#Question id: 4070

#Unit 3. Fundamental Processes

An enhancer

a. can be located upstream of a promoter.

b. can be located downstream of a promoter.

c. can be located a variable distance from the promoter.

d. is always located within 1 kb of the promoter.

e. can be cell-type-specific.

TLS Online TPP Program

#Question id: 4071

#Unit 3. Fundamental Processes

The fact that a specific protein leaves a “footprint” on a DNA molecule is indicative of

a. a lack of interaction between the specific protein and DNA.

b. protection from DNAse by the specific protein.

c. binding of the specific protein to all types of DNA.

d. binding of the specific protein to a specific sequence of DNA.

TLS Online TPP Program

#Question id: 4072

#Unit 3. Fundamental Processes

The C-terminal activation domain of transcriptional activators is capable of

a. binding to DNA. 

b. stimulating transcription.

c. interaction with other transcriptional machinery.

d. functioning in a fusion with a DNA-binding domain from an unrelated transcriptional activator.

TLS Online TPP Program

#Question id: 4073

#Unit 3. Fundamental Processes

The expression of which gene(s) is (are) regulated by promoter proximal pausing?

TLS Online TPP Program

#Question id: 4074

#Unit 3. Fundamental Processes

The promoter sequences of RNA polymerase III-transcribed genes are located

TLS Online TPP Program

#Question id: 4075

#Unit 3. Fundamental Processes

Pre-mRNA molecules

a. exist as free RNA molecules in eukaryotic cells.

b. are associated with an abundant set of nuclear proteins.

c. are mostly located in the cytoplasm.

d. are located in the nucleus.