After menopause, hormone replacement therapy with estrogen-like compounds is effective in preventing the progression of osteoporosis. What is the mechanism of their protective effect?

TLS Online TPP Program

#Question id: 28515

#Unit 5. Developmental Biology

Which of the following is correct prediction, If an extra AER is grafted onto an existing limb bud?

TLS Online TPP Program

#Question id: 28516

#Unit 5. Developmental Biology

The two-experiment performed by a scientist with a forelimb mesenchyme and seeing their results;

I-leg mesenchyme is placed directly beneath the wing AER

II-limb mesenchyme is replaced by non-limb mesenchyme beneath the AER

Conclusion of these experiment are seeing; 

a) distal hindlimb structures develop at the end of the limb

b) supernumerary structures are formed, usually toward the distal end of the limb

c) the AER regresses and limb development ceases

Select the correct result about these experiments-

TLS Online TPP Program

#Question id: 28517

#Unit 5. Developmental Biology

What would be the effect of FGFs and Wnts treatment on the ‘bone formation’ of young limb bud mesenchyme?

TLS Online TPP Program

#Question id: 28518

#Unit 5. Developmental Biology

Achondroplasia is caused by base-pair substitution mutation that converts ____

TLS Online TPP Program

#Question id: 28519

#Unit 5. Developmental Biology

A Condition wherein chondrocytes stop proliferating earlier than usual, resulting in short limbs, that causes

TLS Online TPP Program

#Question id: 28520

#Unit 5. Developmental Biology

Thanatophoric dysplasia is caused by the mutation in which of the following;

a) base-pair substitution that converts glycine to arginine 

b) extracellular domain of the FgfR3 protein

c) transmembrane domain of the FgfR3 protein

d) tyrosine kinase intracellular domain of the FgfR3 protein