TLS Online TPP Program

#Question id: 863


Ubiquitinated proteins are proteolytically degraded in an ATP-dependent process mediated by a large (∼2500 kD, 26S) multiprotein complex named the 26S proteasome;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. A hollow cylindrical core, known as the 20S proteasome, which is covered at one or both ends by a 19S cap.

  2. The yeast 20S proteasome, which is closely similar to other eukaryotic 20S proteasomes, is composed of Ten different types of α-like subunits.

  3. The yeast 20S proteasome, which is closely similar to other eukaryotic 20S proteasomes, is composed of seven different types of α-like subunits and seven different types of β-like subunits.

  4. The α-type subunits and the β-type subunits are structurally similar, only three of the β-type subunits have proteolytic activity.

    Choose any one incorrect option.

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TLS Online TPP Program

#Question id: 14834

#Unit 5. Developmental Biology

Process by which a spatial and temporal pattern of cell activities is organized within the embryo so that a well-ordered structure develops:

TLS Online TPP Program

#Question id: 14835

#Unit 5. Developmental Biology

There are three main ways in which inducing signals may be passed between cells EXCEPT

TLS Online TPP Program

#Question id: 14836

#Unit 5. Developmental Biology

In the case of the French flag model. we assume a source of morphogen at one end and a sink at the other and that the concentrations of morphogen at both ends are kept constant but are different from each other. If the cells can respond to threshold concentrations of the morphogen, Thresholds can represent the
a. amount of morphogen that must bind to receptors to activate an intracellular signaling system. 
b. concentrations of transcription factors required to activate particular genes.
c. concentration at any point effectively provides positional information.
d. amount of morphogen that must bind to receptors to inactivate an extracellular signaling system.

TLS Online TPP Program

#Question id: 14837

#Unit 5. Developmental Biology

Each of the three major strategies of cell specification summarized in TABLE  offers a different way of providing each embryonic cell with a set of determinants (often transcription factors) that will activate specific genes and cause the cell to differentiate into a particular cell type:

Choose right combinations;

TLS Online TPP Program

#Question id: 14838

#Unit 5. Developmental Biology

Sequence of amphibian lens induction postulated by experiments on embryos of the frog Xenopus laevis ; EXCEPT

TLS Online TPP Program

#Question id: 14839

#Unit 5. Developmental Biology

Given are certain facts which define ‘specification’ of a developing embryo.
 A. At the specification stage, commitment to cell identity is labile.
 B. At the specification stage, cell is capable of differentiating autonomously.
 C. The cell “knows” very early what it is to become without interacting with other cells.
 D. A phase where inductive signals trigger cell to determines their fate.
 Which of the above statements best define specification?