Prion protein is a normal constituent of brain tissue in all mammals which of the following statements are correct regarding prion protein

a) Strains of mice lacking the gene for PrP suffer no obvious ill effect

b) Illness occurs only when the normal cellular PRP or prpc occurs in an altered confirmation called PrPsc

c) The interaction of prpsc with the prpc converts the letter to prpsc initiating a Domino effect in which more and more the brain proteins converted to the disease causing form

d) the structure of prpsc is very different with much of the structure converted to amyloid like Alpha sheet.

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#Question id: 12951

#Unit 7. System Physiology – Animal

If the cortical collecting tubule tubular fluid inulin concentration is 40 mg/100 ml and plasma concentration of inulin is 2.0 mg/100 ml, what is the approximate percentage of the filtered water that remains in the tubule at that point?

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#Question id: 12952

#Unit 7. System Physiology – Animal

Which of the following changes would tend to increase Ca2+ reabsorption in the renal tubule?

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#Question id: 12953

#Unit 7. System Physiology – Animal

 Which of the following diuretics inhibits Na+-2Cl−-K+ co-transport in the loop of Henle as its primary action?

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#Question id: 12954

#Unit 7. System Physiology – Animal

A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?

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#Question id: 12955

#Unit 7. System Physiology – Animal

Which of the following would tend to decrease GFR by more than 10% in a normal kidney?

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#Question id: 12956

#Unit 10. Ecological Principles

For  nearly 200  years, biogeographers have  noted that  the  tropics  have  more terrestrial species than  temperate regions. Which of the following is NOT a plausible explanation for this pattern?