TLS Online TPP Program

#Question id: 878


Can a peptide bind more strongly to an unfolded than the same protein in a folded state?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. It will depend on the balance of favourable interactions (enthalpy) versus loss in conformational entropy. For the folded protein, the loss in conformational entropy is less upon binding.

  2. If the increased interactions for the unfolded protein can less than compensate the increased loss in conformational entropy then the net Gibbs free energy will be favourable.

  3. The unfolding do not cause the the appearance of hydrophobic sites of the surface of protein, so if the interaction of the peptide with the protein is depending on the hydrophobic site.

  4. If the binding site changed due to unfolding the binding will be stronger.

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TLS Online TPP Program

#Question id: 12626

#Unit 6. System Physiology – Plant

Strigolactone biosynthesis  takes place in____

TLS Online TPP Program

#Question id: 12627

#Unit 6. System Physiology – Plant

Strigolactones are synthesized from β-carotene,  synthesis of the intermediate carlactone, beyond which strigolactone biosynthesis diverges is takes place____
a) in a species-specific manner
b) in Non-species specific manner
c) Divergence is attributed to the functional diversity of MAX1 cytochrome P450 isoforms, which act on carlactone
d) Divergence is attributed to the functional diversity of MAX1 cytochrome P450 isoforms, which act on 5-Deoxystrigol
Which of the following combination from the above statement is true?

TLS Online TPP Program

#Question id: 12628

#Unit 6. System Physiology – Plant

Brassinosteroids  biosynthesis precursor  is______

TLS Online TPP Program

#Question id: 12629

#Unit 6. System Physiology – Plant

During the biosynthesis of brassinosteroid derived from the sterol campesterol follows two types of the pathway
i) Late C-6 oxidation pathway
ii) Early C-6 oxidation pathway
follows  the different reaction performing in each  pathways such as,
a) Campesterol → Campestanol →6-Deoxoteasterone→ Castasterone→Teasterone →Brassinolide
b) Campesterol → 6-Oxocampestanol →Cathasterone →Teasterone → Castasterone →Brassinolide
c) Campesterol → Campestanol →6-Deoxocathasterone →6-Deoxoteasterone → Castasterone →Brassinolide
Find the correct combination of the each oxidation pathway with its performing sequences;

TLS Online TPP Program

#Question id: 12630

#Unit 6. System Physiology – Plant

Bioactive brassinosteroid levels are also modulated by a variety of inactivation or catabolic reactions, except;
a) epimerization
b) hydroxylation
c) Phosphorylation
d) Sulfonation
e) Ubiquitinylation
f) Conjugation to glucose or lipids

TLS Online TPP Program

#Question id: 12631

#Unit 6. System Physiology – Plant

The receptor  of brassinosteroid are the  largest class of plant receptor kinases, which is localize to the plasma membrane as transmembrane protein;