#Question id: 861
#Unit 1. Molecules and their Interaction Relevant to Biology
Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-
|
A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of |
i. Only 2 to 3 minutes, |
|
B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of |
ii. >10 hours in prokaryotes iii. >20 hours in eukaryotes. |
#Question id: 862
#Unit 1. Molecules and their Interaction Relevant to Biology
Match the following
| lysosomal protein degradation pathways | Found in | |
| 1. Nonselective | a-well-nourished cells | i-containing the pentapeptide Lys-Phe-Glu-Arg-Gln |
| 2- Selective | b-starving cells |
#Question id: 863
#Unit 1. Molecules and their Interaction Relevant to Biology
Ubiquitinated proteins are proteolytically degraded in an ATP-dependent process mediated by a large (∼2500 kD, 26S) multiprotein complex named the 26S proteasome;
#Question id: 864
#Unit 1. Molecules and their Interaction Relevant to Biology
Which one is not the appropriate function of Heat Shock Proteins;
#Question id: 865
#Unit 1. Molecules and their Interaction Relevant to Biology
In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______
#Question id: 866
#Unit 1. Molecules and their Interaction Relevant to Biology
Which of the following is known as Sanger’s reagent