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TLS Online TPP Program

#Question id: 12019

Chickadees were given an opportunity to store seeds in 72 possible storage sites consisting of holes drilled in small trees that had been placed in an aviary. Typically, the seeds were placed in only 4 or 5 storage sites. The chickadees were then removed from the aviary, the seeds removed from the storage sites, and each hole covered. A day later, the chickadees were returned to the aviary and they spent nearly 5 times as long pulling at the covers on storage sites than at the covers on sites where they had not stored food. This experiment indicates that chickadees

#Unit 10. Ecological Principles
  1. Use auditory cues to find stored food
  2. Have a spatial memory that enables them to locate storage sites
  3. Have a propensity to inspect and pull at the covers wherever they are located
  4. Cannot find a storage site if they cannot see the food 
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TLS Online TPP Program

#Question id: 4287

#Unit 3. Fundamental Processes

How the mTOR pathway increases the protein synthesis?
TLS Online TPP Program

#Question id: 4288

#Unit 3. Fundamental Processes

During eukaryotic protein synthesis, stress conditions result in activation of specific kinases leading to phosphorylation of a key translation initiation factor that inhibits protein synthesis from a large number of cellular mRNA. Which one of the following factors is the kinase?
TLS Online TPP Program

#Question id: 4289

#Unit 3. Fundamental Processes

Match the Following

A. fidelity of codon recognition

1. involves two adjacent adenine residues in the 16S rRNA component located

within the A-site of the small subunit. These bases form hydrogen bonds with

the minor groove of each correct base pair formed between the anticodon and

the first two bases of the codon in the A-site

B. kinetic selectivity

2. Even a single mismatch in the codon–anticodon base pairing alters the position of EF-Tu, reducing its ability to interact with the factor-binding center. This, in turn, leads to a dramatic reduction in EF-Tu GTPase activity

C. Accommodation

3. When the charged tRNA is first introduced

into the A-site in a complex with EF-Tu-GTP, its 30 end is distant from the site of peptide-bond formation. To participate successfully in the peptidyl transferase reaction, the tRNA must rotate into the peptidyl transferase center of the large subunit in a process

TLS Online TPP Program

#Question id: 4290

#Unit 3. Fundamental Processes

23S rRNA catalyze peptide-bond formation explained by the model of proton shuttle given in figure.

 Which of the following statements is/are CORRECT for this model?

A. Base pairing between the 23S rRNA and the CCA ends of the tRNAs in the A- and P-sites positions is crucial for this reaction

B. This catalytic mechanism involves entropy

C. 2’-OH of the P-site tRNA act as part of a “proton shuttle”

D. it is a protein that catalyses peptide bond formation
TLS Online TPP Program

#Question id: 4291

#Unit 3. Fundamental Processes

There are two classes of release factors. Match the following

A. Class I release factors

1. recognize the stop codons and trigger hydrolysis of the peptide chain from the tRNA in the P-site.

B. Class II release factors

2. stimulate the dissociation of the class I factors from the ribosome after release of the polypeptide

chain.

C. RF1

3. recognizes the stop codon UAG

D. RF2

4. recognizes the stop codon UGA.

E. RF1 & RF2

5. UAA

TLS Online TPP Program

#Question id: 4292

#Unit 3. Fundamental Processes

Termination of prokaryotic translation take place in three set of events. Match the following

A. glycine glycine glutamine, GGQ and RF3-GTP

1. That is essential for polypeptide release in first step, release of class I RF

B. RRF & EF-G

2. the tRNAs and the mRNA must be removed from the ribosome, and the ribosome must dissociate into its large and small subunits.

C. IF3

3. Release of ribosome