Which pair of alternatives is highlighted by the life cycle of the cellular slime molds, such as Dictyostelium?

TLS Online TPP Program

#Question id: 15360

#Unit 4. Cell Communication and Cell Signaling

The cytochrome P450 constitute a superfamily of heme-containing enzymes that occur in nearly all living organisms, from bacteria to mammals, These monooxygenases, which in animals are embedded in the endoplasmic reticulum membrane, catalyze reactions of the sort

                  RH + O₂ + 2 H⁺ + 2e⁻ → ROH + H₂O 

The electrons (e−) are supplied by NADPH, which passes them to cytochrome P450’s heme prosthetic group via the intermediacy of the enzyme NADPH P450 reductase. Here RH represents a wide variety of usually lipophilic compounds for which the different cytochromes P450 are specific. They include

a. polycyclic aromatic hydrocarbons 

b. polycyclic biphenyls

c. frequently carcinogenic compounds that are present in tobacco smoke, broiled meats, and other pyrolysis products

d. which were widely used in electrical insulators and as plasticizers and are also carcinogenic.

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#Question id: 15361

#Unit 4. Cell Communication and Cell Signaling

The chemical benzo(a)pyrene, found in cigarette smoke as well as in coal tar, undergoes metabolic activation in the lungs to form a potent mutagen that mainly, causes conversion of guanine (G) to thymine (T) bases, a transversion mutation, When applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including inactivating mutations of the p53 gene, at codon number______

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#Question id: 15362

#Unit 4. Cell Communication and Cell Signaling

Aflatoxin a fungal metabolite found in moldy grains, induces

TLS Online TPP Program

#Question id: 15363

#Unit 4. Cell Communication and Cell Signaling

Epithelial-to-mesenchymal transition (EMT) is thought to play a crucial role during the process of metastasis in some cancers, Snail and Twist are the two transcription factors, function as EXCEPT

TLS Online TPP Program

#Question id: 15364

#Unit 4. Cell Communication and Cell Signaling

In normal cells, FOS and MYC mRNAs and the proteins they encode are intrinsically unstable and degrade rapidly after the genes are transcribed, Conversion of the MYC proto-oncogene into an oncogene can occur by different mechanisms, Other members of this protein set include MAD, MAX, and MNT, choose incorrect statement regarding this,

TLS Online TPP Program

#Question id: 15365

#Unit 4. Cell Communication and Cell Signaling

The MDM2 protein in its active form can form a complex with p53, inhibiting the transcription factor and causing p53 ubiquitinylation and subsequent proteasomal degradation, ATM phosphorylates MDM2 to inactivate it, causing increased stabilization of p53, but there is one another gene or key regulator which controls the level of MDM2;