#Question id: 32247
#Unit 2. Cellular Organization
#Question id: 2986
#Unit 2. Cellular Organization
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?
#Question id: 1086
#Unit 4. Cell Communication and Cell Signaling
What is the most likely mechanism by which testosterone functions inside a cell?
#Question id: 1288
#Unit 4. Cell Communication and Cell Signaling
Which extracellular matrix component is expressed in a cell-specific manner and binds to the tripeptide sequence Arg-Gly-Asp?
#Question id: 31125
#Unit 2. Cellular Organization