The appropriate folding of a newly translated product is essential, and continual misfolding often leads to disease, especially in vertebrates. This misfolding, particularly in the situation of prion diseases, may be due to

TLS Online TPP Program

#Question id: 10933

#Unit 1. Molecules and their Interaction Relevant to Biology

Imidazole ring is the characteristic of which amino acid

TLS Online TPP Program

#Question id: 12030

#Unit 7. System Physiology – Animal

A significant contribution of intestinal bacteria to human nutrition is the benefit of bacterial:

TLS Online TPP Program

#Question id: 14686

#Unit 4. Cell Communication and Cell Signaling

This member of the AKAP family, designated mAKAP, anchors both PDE and the regulatory subunit  of PKA to the nuclear membrane, maintaining them in a negative feedback loop that provides close local control of the ATP level and PKA activity.

B- The basal level of PDE activity in the presence of hormone (resting state) keeps cAMP levels below those necessary for PKA activation. 

C- Activation of β-adrenergic receptors causes an increase in cAMP to a level in excess of that which can be degraded by PDE. 

D- The resulting binding of cAMP to the R subunits of PKA releases the active catalytic (C) subunits into the cytosol. Some C subunits enter the nucleus, where they phosphorylate and thus activate certain transcription factors . Other C subunits phosphorylate PDE, stimulating its catalytic activity.

E-  Active PDE hydrolyzes cAMP, thereby driving cAMP levels back to basal levels and causing re-formation of the inactive PKA C-R complex. Subsequent de-phosphorylation of PDE returns the complex to the resting state.

TLS Online TPP Program

#Question id: 18761

#Unit 13. Methods in Biology

Which of the following process occurs between DNA molecules of very similar sequences?

TLS Online TPP Program

#Question id: 33401

#Unit 1. Molecules and their Interaction Relevant to Biology

Four-bladed B propeller of Collagenase is made of