#Question id: 2915
#Unit 2. Cellular Organization
The structural maintenance of chromosome (SMC) proteins are extended proteins that form defined pairs by interacting through lengthy coiled-coil domains. Together with non-SMC proteins, they form multiprotein complexes that act to link two DNA helices together. Identify the SMC proteins in the figure given below and match them with their respective subunits.
i. Blue – Cohesin made up of Smc 1 and Smc 2 proteins.
ii. Green – Condensin made up of Smc 3 and Smc 4 proteins.
iii. Blue – Condensin made up of Smc 2 and Smc 4 proteins.
iv. Green – Cohesins made up of Smc 1 and Smc 3 proteins.
v. Blue – Condensin made up of Smc 1 and Smc 3 proteins.
vi. Green – Cohesins made up of Smc 2 and Smc 4 proteins.
#Question id: 2916
#Unit 2. Cellular Organization
Which of the following statement is INCORRECT regarding the packaging of DNA into higher order chromatin structure?
#Question id: 2917
#Unit 2. Cellular Organization
With respect to the interconversion between open and condensed chromatin shown below: Which of the directions (i) or (ii) would you anticipate would be the consequence of the following types of chromatin modification?
#Question id: 2918
#Unit 2. Cellular Organization
Some DNA sequences in our cells have high frequencies of methylated cytosines (hypermethylation); some others have a low frequency of methylated cytosines (hypomethylation). Which of the two methylation states best describes the kind of sequences listed below?
I. Satellite DNA in pericentromeric heterochromatin
II. Promoters
III. Dispersed transposon repeats
IV. CpG islands
V. Enhancers
#Question id: 2919
#Unit 2. Cellular Organization
Topoisomerases play the essential role of unlinking the DNA molecules to allow them to separate into the two daughter cells for cell division. Which of the following statements regarding the mechanism of topoisomerases is INCORRECT?
#Question id: 2920
#Unit 2. Cellular Organization
Which of the following statements is INCORRECT with respect to the organization and content of the human genome?