TLS Online TPP Program

#Question id: 12185


Mitotic CDKs affect nuclear envelope components by specific mechanism. Which of the following statement is not related to this mechanism?

#Unit 2. Cellular Organization
  1. The CDKs phosphorylate specific nucleoporins, which causes nuclear pore complexes to dissociate into subcomplexes during prophase. 
  2. Phosphorylation of integral membrane proteins of the inner nuclear membrane causes depolymerization of the lamin intermediate filaments.
  3. The weakening of the associations between the inner nuclear membrane proteins and the nuclear lamina and chromatin allows sheets of inner nuclear membrane to retract into the endoplasmic reticulum, which is continuous with the outer nuclear membrane.
  4. Mitotic CDKs induce the formation of the mitotic spindle. The function of the mitotic spindle is to segregate chromosomes so that the sister chromatids separate from each other and are moved to opposite poles of the cell.