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TLS Online TPP Program

#Question id: 12187

How cells know whether sister kinetochores are properly attached to the mitotic spindle?

#Unit 2. Cellular Organization
  1. When sister chromatids are correctly attached to microtubules, their kinetochores are under tension. Mitotic spindle attached to the kinetochores pull at them, and the cohesin molecules that hold the sister chromatids together withstand these forces, creating tension at kinetochores.
  2. When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. One kinetochore attaches to microtubules emanating from two opposite spindle poles.
  3. When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. Both sister kinetochores attach to microtubules emanating from the same spindle pole.
  4. When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. Only one of the two sister kinetochores attaches to microtubules.
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TLS Online TPP Program

#Question id: 12183

#Unit 2. Cellular Organization

Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?
TLS Online TPP Program

#Question id: 33692

#Unit 2. Cellular Organization

Gene families with the highest number of pseudogenes are
A. Olfactory Receptor (OR) 
B. Immunoglobulin (Ig)
C. Zinc Finger Protein (ZNF)
D. Globin gene family
TLS Online TPP Program

#Question id: 5196

#General Aptitude

In the exam, one noticed that his answer and his friend’s answer differ, and his friend’s answer had a decrease of 315 . this happened because instead of multiplying with 23, he multiplied with 32. What can be the original  answer?
TLS Online TPP Program

#Question id: 15265

#Unit 2. Cellular Organization

The growth of microorganisms in a food product is influenced by the availability of
TLS Online TPP Program

#Question id: 4082

#Unit 3. Fundamental Processes

Which of the following is (are) not involved in alternative splicing in eukaryotes?