TLS Online TPP Program

#Question id: 12271


A young woman comes to the emergency room with a vertebral compression fracture. Radiographs of the spine indicate generalized demineralization. She is vegetarian, does not smoke or drink alcohol, has normal plasma potassium concentration of 5.4 mEq/L, sodium concentration of 136 mEq/L, plasma calcium concentration is 7.0 mg/dL. Her vitamin D3 value is several times greater than normal, although her 1,25-dihydroxycholecalciferol concentration is at the lower limit of detectability. She has been in renal failure for the last 5 years and undergoes hemodialysis three times each week. What is the cause of her low 1,25-dihydroxycholecalciferol level?

#Unit 7. System Physiology – Animal
  1. Metabolic acidosis
  2. Metabolic alkalosis
  3. She is unable to form 1,25-dihydroxycholecalciferol because of her extensive kidney disease
  4. She is being dialyzed with a dialysis fluid without calcium