A 45-year-old man adds lots of high-fiber wheat and bran foods to his diet to reduce his cholesterol. He loses 30 lb on the new diet, but has undesirable side effects such as stomach cramps, flatulence, and diarrhea. His gastroenterologist diagnoses a syndrome called gluten-enteropathy or celiac sprue. Which of the following is decreased in this man?

TLS Online TPP Program

#Question id: 24492

#Unit 3. Fundamental Processes

Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site. So, in below table the complex and their events are given match them correctly .

TLS Online TPP Program

#Question id: 24493

#Unit 3. Fundamental Processes

Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site. 

1. U2 addition to base pair with the branch site in the presence of ATP

2. U1 and U4 release Formation of the catalytic center in which U6 base pairs with the 5' splice site; U6 also base pairs with U2; U2 remains base paired with the branch site; U5 interacts with both exons through its loop.

So, 1 and 2 are the event of complex formation which are 

TLS Online TPP Program

#Question id: 24494

#Unit 3. Fundamental Processes

U1 and U4 release Formation of the catalytic center in which U6 base pairs with the 5' splice site; U6 also base pairs with U2; U2 remains base paired with the branch site; U5 interacts with both exons through its loop is the characterstic of one of the stage during splicing, which is 

TLS Online TPP Program

#Question id: 24495

#Unit 3. Fundamental Processes

Which of the following step of splicing involves ATP

TLS Online TPP Program

#Question id: 24496

#Unit 3. Fundamental Processes

Lariat formation is characterized by

TLS Online TPP Program

#Question id: 24497

#Unit 3. Fundamental Processes

Choose the incorrect statement 

A. Lariat formation is characterized by 2’-5’ phosphodiester bond

B. Lariat formation is characterized by 3’-5’ phosphodiester bond

C. Group II mitochondrial introns are excised by the same mechanism as nuclear pre-mRNAs via a lariat that is held together by a 2’–5’ bond.

D. Group II mitochondrial introns are excised by the different  mechanism as nuclear pre-mRNAs via a lariat that is held together by a 2’–5’ bond.