TLS Online TPP Program

#Question id: 12277


A 45-year-old man adds lots of high-fiber wheat and bran foods to his diet to reduce his cholesterol. He loses 30 lb on the new diet, but has undesirable side effects such as stomach cramps, flatulence, and diarrhea. His gastroenterologist diagnoses a syndrome called gluten-enteropathy or celiac sprue. Which of the following is decreased in this man?

#Unit 7. System Physiology – Animal
  1. Absorption of nutrients
  2. Digestion of fat
  3. Stool carbohydrates
  4. Stool fat
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TLS Online TPP Program

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

COLUMN I

COLUMN II

 

 

 

  ΔH

ΔS

ΔG = ΔH – TΔS

1.

+

a. The reaction is both enthalpically and entropically opposed. It is nonspontaneous (endergonic) at all temperatures.

2.

 −

− 

b. The reaction is enthalpically opposed (endothermic) but entropically favored. It is spontaneous only at temperatures above T = ΔH/ΔS.

3.

+

+

c. The reaction is enthalpically favored but entropically opposed. It is spontaneous only at temperatures below T = ΔH/ΔS.

4.

+

d. The reaction is both enthalpically favored (exothermic) and entropically favored. It is spontaneous (exergonic) at all temperatures.

TLS Online TPP Program

#Question id: 674

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline is not often found in a-helices of proteins because it

TLS Online TPP Program

#Question id: 1520

#Unit 1. Molecules and their Interaction Relevant to Biology

Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 835

#Unit 1. Molecules and their Interaction Relevant to Biology

The minor clefts and gullies on the sides of the funnel that will be false energy minima, it represents,

TLS Online TPP Program

#Question id: 837

#Unit 1. Molecules and their Interaction Relevant to Biology

Increasing order of free energy in unfolded to folded conformation of the proteins, the correct order is,

TLS Online TPP Program

#Question id: 2636

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following events occur when E. coli is starved for tryptophan?

I.  The ribosome translates leader peptide completely

II. Transcription reads through attenuator into trp EDCBA

III. Tryptophanyl tRNA is not formed

IV. A stem loop structure involving regions 3 and 4 is formed at attenuator site