Given  some  statements  about auxin  signal  transduction  pathway;

a) ARFs bind the AuxRE stably, must form dimers promote transcription by binding to two AuxREs arranged in a palindrome

b) inactive heterodimers may act to inhibit ARF–AuxRE binding, thereby blocking either gene activation or repression

c) Protein encodes the AUX/IAA gene family can inhibit the transcription of early auxin response genes by forming inactive heterodimers with ARFs

d) Auxin induces the transcription of the early response genes by promoting the proteolytic degradation of the inhibitory AUX/IAA proteins so that active ARF dimers can form

e) AUX/IAA turnover to involve ubiquitination by a ubiquitin ligase and proteolysis by the massive 26S proteasome complex

f) A negative feedback loop is introduced into the pathway by virtue of the fact that one of the gene families turned on by auxin is AUX/IAA, which inhibits the response.

Find out the correct sequence from the following above statements;

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#Question id: 28768

#Unit 2. Cellular Organization

Given following paths from different sources feed substances into lysosomes for digestion, find out the A, B and C?

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#Question id: 28769

#Unit 2. Cellular Organization

Autophagy occurs in the following sequence of steps___

a) Nucleation of autophagosome formation by ATG9

b) Digestion of the inner membrane and the luminal contents of the autophagosome.

c) Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

d) Induction by inhibition of mTOR complex 1

e) Closure of the membrane cup to form autophagosome

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#Question id: 28770

#Unit 2. Cellular Organization

Autophagy can be either;

I- Nonselective autophagy

II- Selective autophagy

a) Closure of the membrane cup to form autophagosome

b) a bulk portion of cytoplasm is sequestered in autophagosomes

c) used to destroy invading microbes

d) Nucleation of autophagosome formation by ATG1

Find out the correct match statements of about selective as well as nonselective autophagy?

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#Question id: 28771

#Unit 2. Cellular Organization

Which of the following sorting signal that directs lysosomal hydrolases from the TGN to the late endosome?

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#Question id: 28772

#Unit 2. Cellular Organization

M6P residues are generated in the cis-Golgi by which of the following Golgi-resident enzymes?

a) N-acetylglucosamine (GlcNAc) phosphotransferase

b) ornithine transcarbamylase 

c) Phosphodiesterase

d) Catalases

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#Question id: 28773

#Unit 2. Cellular Organization

Which of the following coat protein complex specialized for endosome-to-TGN transport, also responsible for recycling the M6P receptor to the TGN?