Given  some  statements  about auxin  signal  transduction  pathway;

a) ARFs bind the AuxRE stably, must form dimers promote transcription by binding to two AuxREs arranged in a palindrome

b) inactive heterodimers may act to inhibit ARF–AuxRE binding, thereby blocking either gene activation or repression

c) Protein encodes the AUX/IAA gene family can inhibit the transcription of early auxin response genes by forming inactive heterodimers with ARFs

d) Auxin induces the transcription of the early response genes by promoting the proteolytic degradation of the inhibitory AUX/IAA proteins so that active ARF dimers can form

e) AUX/IAA turnover to involve ubiquitination by a ubiquitin ligase and proteolysis by the massive 26S proteasome complex

f) A negative feedback loop is introduced into the pathway by virtue of the fact that one of the gene families turned on by auxin is AUX/IAA, which inhibits the response.

Find out the correct sequence from the following above statements;

#Question id: 68

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following functional groups given in column I with their respective representatives given in column II.

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

#Question id: 674

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline is not often found in a-helices of proteins because it

#Question id: 1520

#Unit 1. Molecules and their Interaction Relevant to Biology

Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

#Question id: 27941

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 27942

#Unit 1. Molecules and their Interaction Relevant to Biology