Review the formula for effective population size. Imagine a population of 1,000 small rodents. Of these, 300 are breeding females, 300 are breeding males, and 400 are nonbreeding  juveniles.  What is the effective  population size?

#Question id: 4423

#Unit 1. Structure and Function of Biomolecules

Each repeat unit within the nuclear ribosomal gene cluster of eukaryotes (rDNA) contains

#Question id: 10308

#Unit 1. Structure and Function of Biomolecules

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

#Question id: 804

#Unit 1. Structure and Function of Biomolecules

With respect to microRNAs, which, if any, of the following statements, is false?

a) A microRNA normally works by binding to perfectly complementary sequences within an RNA transcript, usually an mRNA.

b) Like the great majority of mRNAs an miRNA is usually produced as a larger precursor RNA that is capped and has a 3’ poly(A) tail.

c) The precursor miRNA undergoes different types of post-transcriptional cleavage by endoribonucleases that are specific for double-stranded target sequences.

d) A nuclear endoribonuclease called dicer cleaves the miRNA precursor so that it forms a stem-loop RNA.

#Question id: 27530

#Unit 1. Structure and Function of Biomolecules

Match the Group 1 with appropriate solution of Group 2

#Question id: 30115

#Unit 1. Structure and Function of Biomolecules

The antibacterial trimethoprim is an inhibitor of 

#Question id: 10306

#Unit 1. Structure and Function of Biomolecules

pyruvate dehydrogenase (PDH) complex requires five different coenzymes or prosthetic groups and these enzymesalso require four different vitamins in human nutrition are vital components of this system: