Following statements are regarding to Kinetochore-microtubule interaction in S. cerevisiae.

A. In the simple kinetochore of S. cerevisiae, a protein complex called CBF3 associates with specialized, centromere-specific form of histone H3, called CENP-A.

B. The Ndc80 complexes initially make lateral interactions with a spindle microtubule and subsequently interact with a Dam1 complex, which forms a ring around the end of the microtubule. This interaction results in an end-on attachment of the centromere to the

spindle microtubule.

C. Microtubules that “capture” kinetochores are selectively stabilized by a reduction in the rate of catastrophes, which increases the chance that the attachment will persist.

D. With the two kinetochores attached to opposite poles, the duplicated chromosome is now under tension, being pulled in both directions by the one sets of kinetochore microtubules.

Which of the following combinations is correct?

TLS Online TPP Program

#Question id: 19720

#Unit 3. Fundamental Processes

Tetraplex structure is the characteristics of telomere, choose the incorrect statement regarding this quartets

TLS Online TPP Program

#Question id: 19721

#Unit 3. Fundamental Processes

Three stacked G quartets are the characteristics of 

TLS Online TPP Program

#Question id: 19722

#Unit 3. Fundamental Processes

Telomerase, a reverse transcriptase that contains an RNA template, repeatedly adds 

TLS Online TPP Program

#Question id: 19723

#Unit 3. Fundamental Processes

Reduction in the telomerase activity after the cell cycle is the notion of 

a) Cell ageing

b) Senescence 

c) Apoptosis

TLS Online TPP Program

#Question id: 19733

#Unit 3. Fundamental Processes

Extensive shortening of telomeres eventually leads to 

TLS Online TPP Program

#Question id: 19734

#Unit 3. Fundamental Processes

Some of the statements are given regarding shelterin choose the correct 

a) Shelterin is the complex of telomeric protein

b) Shelterin functions to protect telomeres from DNA damage repair pathways

c) In mammals, six telomeric proteins (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1) comprises a complex.

d) Shelterin also regulate telomere length control by telomerase