In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 1 is a carrier of oculocutaneous albinism? 

TLS Online TPP Program

#Question id: 19740

#Unit 3. Fundamental Processes

Choose the correct statement

a) Telomeric RNA component is encoded by TLC1 in yeast, and hTERC in humans

b) Telomeric RNA component is encoded by hTERC in yeast, and TLC1 in humans

c) Telomerase protein component with catalytic activity is encoded by EST2 in yeast, hTERT in humans

d) Telomerase protein component with catalytic activity is encoded by hTERT in yeast, EST2 in humans

TLS Online TPP Program

#Question id: 19741

#Unit 3. Fundamental Processes

Telomerase protein component with catalytic activity is encoded by 

TLS Online TPP Program

#Question id: 19742

#Unit 3. Fundamental Processes

Match the following 

Organism	Size of RNA component
A) Tetrahymena	i) 451 bases long
B) Humans	ii) 1.3 kb in yeast
C) Yeast	iii) 159 bases long

TLS Online TPP Program

#Question id: 19743

#Unit 3. Fundamental Processes

Which proteins regulates number of repeats in RNA component for telomere lengths

TLS Online TPP Program

#Question id: 19744

#Unit 3. Fundamental Processes

Which of the following statement is incorrect regarding Cdc 13

TLS Online TPP Program

#Question id: 19745

#Unit 3. Fundamental Processes

Shelterin is the complex of six protein (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1), below some of the statements are given regarding POT1, choose the correct statement 

a) POT1 binding to single-stranded telomere DNA and promote telomere activity.

b) POT1 binding to single-stranded telomere DNA inhibits telomere activity.

c) POT1 acts as antagonist of Cdc13 which inhibits the telomere activity.

d) POT1 helps in recruitment of telomerase