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TLS Online TPP Program

#Question id: 12835

Following statements are regarding to the surveillance mechanism. Which of the following statement is incorrect?

#Unit 2. Cellular Organization
  1. DNA damage leads to the activation of p21, a transcription factor that induces the expression of the gene encoding the CDK inhibitor p53.
  2. When the DNA damage occurs during S phase or in G2, Cdc25C inhibition by Chk1/2 results in the inhibition of mitotic CDKs and hence arrest in G2.
  3. Cells sense DNA replication stress that results in stalling or slowing of replication forks. Such stress triggers activation of the ATR-Chk1 checkpoint pathway and results in downregulation of S phase CDK activity and prevents the firing of late-replicating origins.
  4. ATM halts cell cycle progression by Chk2-mediated inhibition of Cdc25, thus preventing activation of CDKs. This inhibition can occur in G1 or G2.
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TLS Online TPP Program

#Question id: 1650

#Unit 4. Cell Communication and Cell Signaling

Recombination of V, D, and J Ig gene segments:
TLS Online TPP Program

#Question id: 1651

#Unit 4. Cell Communication and Cell Signaling

Ig idiotypes are found:
TLS Online TPP Program

#Question id: 1652

#Unit 4. Cell Communication and Cell Signaling

With reference to the variable Ig domain, which of the following statements is FALSE?
TLS Online TPP Program

#Question id: 1653

#Unit 4. Cell Communication and Cell Signaling

Which of the following statements does NOT apply to IgG?
TLS Online TPP Program

#Question id: 1654

#Unit 4. Cell Communication and Cell Signaling

The low affinity FcγRII IgG receptor:
TLS Online TPP Program

#Question id: 1655

#Unit 4. Cell Communication and Cell Signaling

IgA in seromucus secretions: