TLS Online TPP Program

#Question id: 13040


Which of the following is incorrect about Oligonucleotide Design in A microarray? 

#Unit 13. Methods in Biology
  1. DNA microarrays are generated by fixing oligonucleotides onto a solid support 
  2. The oligonucleotide array slide represents thousands of preselected genes from an organism 
  3. The length of oligonucleotides is typically in the range of twenty-five to seventy bases long 
  4. The oligonucleotides don’t react with cDNA samples
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TLS Online TPP Program

#Question id: 30110

#Unit 1. Molecules and their Interaction Relevant to Biology

The ribose phosphate group of purine nucleotide is taken from which compound?

TLS Online TPP Program

#Question id: 30111

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the source of the C-2 during the de novo biosynthesis of pyrimidines?

TLS Online TPP Program

#Question id: 30112

#Unit 1. Molecules and their Interaction Relevant to Biology

With respect to the de novo synthesis of nucleotides, which one of the following statements is INCORRECT?

TLS Online TPP Program

#Question id: 30113

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate (Asp) is an amino acid with the structure NH2-CH(CH2-COOH)COOH. Given below are biosynthetic processes occurring in cells:
A. protein synthesis
B. de novo synthesis of inosine monophosphate and orotic acid
C. synthesis of adenosine monophosphate from inosine monophosphate
D. glutathione synthesis

Which one of the following options correctly represents all the biosynthetic process( es) wherein Asp is involved as a precursor?

TLS Online TPP Program

#Question id: 30114

#Unit 1. Molecules and their Interaction Relevant to Biology

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of