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TLS Online TPP Program

#Question id: 13163

Following statements are regarding to the interaction between β2-adrenergic receptor and G- protein.

#Unit 4. Cell Communication and Cell Signaling
  1. Binding of ligand to the receptor induces major conformational changes in which there are substantial movements of transmembrane helices 5 and 6 and changes in the structure of the C3 loop; together, these changes create a surface that can bind to a segment of the Gα subunit and when unbound by ligand, the receptor has no surface that is complementary to the G protein and thus cannot bind to it.
  2. Binding of ligand to the receptor induces major conformational changes in which there are substantial movements of transmembrane helices 1 and 4 and changes in the structure of the C3 loop; together, these changes create a surface that can bind to a segment of the Gα subunit and when unbound by ligand, the receptor has no surface that is complementary to the G protein and thus cannot bind to it.
  3. Binding of ligand to the receptor induces major conformational changes in which there are substantial movements of transmembrane helices 5 and 6 and changes in the structure of the C3 loop; together, these changes have no surface that can’t bind to a segment of the Gα subunit and when unbound by ligand, the receptor creates a surface that is complementary to the G protein and thus can bind to it.
  4. Binding of ligand to the receptor induces major conformational changes in which there are substantial movements of transmembrane helices 3, 5, 6 and 7 and changes in the structure of the E2 loop; together, these changes create a surface that can bind to a segment of the Gα subunit and when unbound by ligand, the receptor has no surface that is complementary to the G protein and thus cannot bind to it.
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TLS Online TPP Program

#Question id: 1037

#Unit 4. Cell Communication and Cell Signaling

In a rapidly multiplying bacterial population, cell numbers increase
TLS Online TPP Program

#Question id: 9200

#Unit 9. Diversity of Life Forms

During the inventory of bacterial genes present in the Sargasso Sea, a deep isolated area in the middle of the Atlantic Ocean, a research team concluded that at least 1,800 bacterial species were present. Based on what you might predict about the habitat structure of such an area, what kind of bacterial diversity would you expect to see in tropical coral reef waters?
TLS Online TPP Program

#Question id: 9193

#Unit 9. Diversity of Life Forms

Which of the following best describes the consequences of White-band disease in Caribbean coral reefs?
TLS Online TPP Program

#Question id: 804

#Unit 1. Molecules and their Interaction Relevant to Biology

With respect to microRNAs, which, if any, of the following statements, is false?

a) A microRNA normally works by binding to perfectly complementary sequences within an RNA transcript, usually an mRNA.

b) Like the great majority of mRNAs an miRNA is usually produced as a larger precursor RNA that is capped and has a 3’ poly(A) tail.

c) The precursor miRNA undergoes different types of post-transcriptional cleavage by endoribonucleases that are specific for double-stranded target sequences.

d) A nuclear endoribonuclease called dicer cleaves the miRNA precursor so that it forms a stem-loop RNA.
TLS Online TPP Program

#Question id: 15300

#Unit 5. Developmental Biology

In hippo signaling pathway, the activation of the Cdx2 gene in the trophoblast cells appears to be regulated by the Yap protein, which in turn is a cofactor for the transcription factor Tead4. Tead4 is found in the ________blastocyst