Consider the following statements regarding mutations:

1. A silent mutation is a change in the DNA sequence that does not change the amino acid sequence of the protein.

2. Missense mutations always result in the complete loss of protein function.

3. Frameshift mutations typically occur due to the insertion or deletion of nucleotides in numbers not divisible by three.

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#Question id: 27960

#Biochemistry

Which of the following phenomenon is directly related to repair  

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#Question id: 27961

#Biochemistry

Conversion of Glucose 6-phosphate →  Ribulose 5-phosphate in oxidative phase involves

(a) 2NADP

(b) Removal of 1 CO2

(c) Uses G6PD as enzyme 

(d) No 2NADP is required

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#Question id: 27963

#Biochemistry

Which of the following is completely true about the α-ketoglutarate dehydrogenase complex

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#Question id: 27964

#Biochemistry

Enzymes their location and cofactor along with the inhibitors is given 

a. Citrate synthase Located in Matrix space uses CoA as cofactor and can be inhibited by Monofluoroacetyl-CoA

b. Aconitase Located in Inner membrane uses Fe2+ as cofactor and can be inhibited by Fluoro acétate

c. Isocitrate dehydrogenase Located Matrix space in uses NAD, NADP Mg2+. Mn2+ as cofactor and can be inhibited by ATP

d. Succinate dehydrogenase Located in Inner membrane uses FAD as cofactor and can be inhibited by Malonate, Oxaloacetate

Which of the following is correct

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#Question id: 27966

#Biochemistry

Which of the following acts in the nucleus to regulate the transcription of genes that respond to thyroid hormone.

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#Question id: 27967

#Biochemistry

Malonate is an analog of succinate not normally present in cells, is a strong competitive inhibitor of succinate dehydrogenase, and its addition to mitochondria blocks the activity of the