The genotype r/r ; p/p gives fowl a single comb, R/– ; P/– gives a walnut comb, r/r ; P/– gives a pea comb, and R/– ; p/p gives a rose comb. Which of the following parental genotype would produce 3/8 Walnut comb, 1/8 pea comb, 3/8 rose comb and, 1/8 single comb?

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#Question id: 12492

#Part-A Aptitude & General Biotechnology

A young man with phenylketonuria, who was successfully treated following diagnosis on newborn screening, is planning to start a family with his healthy, unaffected, and unrelated partner, who has no family history of phenylketonuria . Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10 000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

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#Question id: 12493

#Part-A Aptitude & General Biotechnology

Cystic fibrosis shows autosomal recessive inheritance with an incidence of 1 in 2500. The unaffected brother of an affected girl is referred for genetic counseling. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

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#Question id: 12494

#Part-A Aptitude & General Biotechnology

Hunter syndrome is a rare form of mucopolysacchararidosis that differs from all other forms in that it shows X-linked recessive inheritance. A woman with two affected brothers is referred for genetic counselling. Which of the following is correct?

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#Question id: 12495

#Part-A Aptitude & General Biotechnology

Haemophilia A is a severe coagulation disorder that shows X-linked recessive inheritance. Red-green colour blindness also shows X-linked recessive inheritance. A man with both haemophilia A and colour blindness is referred for genetic counseling. Assume that his partner is not a carrier of either of these conditions. Which of the following is correct?

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#Question id: 12496

#Part-A Aptitude & General Biotechnology

A woman who has two brothers and a maternal uncle (her mother's brother) with non-specific X-linked mental retardation is referred for genetic counselling. There are no diagnostic tests available to help determine whether or not she is a carrier. Which of the following is correct?

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#Question id: 12497

#Part-A Aptitude & General Biotechnology

In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?