TLS Online TPP Program

#Question id: 4143


It is possible to convert the Cys that is a part of Cys-tRNACys to Ala by a catalytic reduction.  If the resulting Ala-tRNACys were added to a mixture of (1) ribosomes, (2) all the other tRNAs and amino acids, (3) all of the cofactors and enzymes needed to make protein in vitro, and (4) mRNA for hemoglobin, where in the newly synthesized hemoglobin would the Ala from Ala-tRNACys be incorporated?

#Part-A Aptitude & General Biotechnology
  1. Nowhere; this is the equivalent of a nonsense mutation

  2. Wherever Ala normally occurs

  3. Wherever Cys normally occurs

  4. Wherever either Ala or Cys normally occurs

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TLS Online TPP Program

#Question id: 4481

#Part-B Specialized Branches in Biotechnology

Choose correct statements about recognition mechanism of TBP ;

A. TBP causes the minor groove to be widened to an almost flat conformation

B. It also bends the DNA by an angle of ~120o

C. The interaction between TBP and DNA involves maximum number of hydrogen bonds between the protein and the edges of the base.

D. Much of the specificity is imposed by two pairs of phenylalanine side chains that intercalate between the base pairs at either end of the recognition sequence and drive the strong bend in the DNA.

TLS Online TPP Program

#Question id: 4483

#Part-B Specialized Branches in Biotechnology

TAF42 and TAF62 from Drosophila form a structure similar to that of the

TLS Online TPP Program

#Question id: 4497

#Part-B Specialized Branches in Biotechnology

Elongation, termination of transcription, and RNA processing are interconnected, presumably to ensure their proper coordination,

   Elongation factors

I.    hSPT5

To recruit the 5’ -capping enzyme to the CTD tail of polymerase

 II.   TAT-SF1

To recruits components of the splicing machinery to polymerase with a Ser-2 phosphorylated tail

TLS Online TPP Program

#Question id: 4532

#Part-B Specialized Branches in Biotechnology

Locus control region, or LCR,

TLS Online TPP Program

#Question id: 4718

#Part-B Specialized Branches in Biotechnology

All the following statements about destruction of cyclins are true, except:

TLS Online TPP Program

#Question id: 4719

#Part-A Aptitude & General Biotechnology

When a trait exhibits complete co-dominance rather than complete dominance, a cross between heterozygote results deviation of following;