Which of the following statement is true?

A) PAM matrices are derived from an evolutionary model whereas the BLOSUM matrices consist of entirely direct observations. 

B) Because of BLOSUM matrices have less evolutionary meaning that is why the PAM matrices are used most often for reconstructing phylogenetic trees.

C) BLOSUM matrices are entirely derived from local sequence alignments of conserved sequence blocks, whereas the PAM matrix is based on the global alignment of full-length sequences.

D) BLOSUM matrices are more advantageous in searching databases and finding conserved domains in proteins.

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#Question id: 18677

#Part-A Aptitude & General Biotechnology

Point mutations in DNA, such as occur in a range of human diseases, can be identified by 

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#Question id: 18678

#Part-A Aptitude & General Biotechnology

which of the following technique can be analysed of PCR products from HIV-I allowed the identification of between 200 000 and 500 000 viral particles per cubic centimetre of serum.

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#Question id: 18679

#Part-A Aptitude & General Biotechnology

Chiral compounds can be resolved using

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#Question id: 18680

#Part-A Aptitude & General Biotechnology

DNA from Salmonella species, when digested with the restriction enzyme Xba I, gives around 15 fragments ranging from 25 kb to 680 kb This pattern of fragments, or ‘fingerprint’, is unique to that strain. If the same fingerprint is found from bacteria from other infected people, then it can be assumed that they were all infected from a common source. Thus, by comparing their eating habits, food sources, etc. the source of the infection can be traced to a restaurant, food item. The fingerprints are created and analysed by

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#Question id: 18681

#Part-A Aptitude & General Biotechnology

Highly heterogeneous mixtures of proteins such as cell lysates or tissue extracts should be completely fractionated into individual proteins so as to obtain an overall picture of the protein composition and to enable location of individual proteins. The highest resolution is obtained 

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#Question id: 18682

#Part-A Aptitude & General Biotechnology

Which technique is shown in given representation