TLS Online TPP Program

#Question id: 7154


Cancer is believed to often arise from stem cells, rather than fully differentiated cells. Which of the following are consistent with this view?

#Part-B Specialized Branches in Biotechnology
  1. Stem cells are actively dividing and express few differentiated functions, so they may have fewer changes to undergo than do fully differentiated cells in becoming cancer cells.
  2. DNA replication is necessary for mutations to occur, and stem cells are replicating their DNA whereas differentiated cells are for the most part not replicating their DNA.
  3. Teratocarcinomas are tumors that arise from germ cells or embryonic stem (ES) cells, under certain circumstances, demonstrating that tumors can arise from stem cells without further mutation.
  4. All of the above are reasons that cancer cells may more readily arise from stem cells than from fully differentiated cells.