#Question id: 4392
#Part-A Aptitude & General Biotechnology
X chromosome inactivation in mammals is mediated by
#Question id: 4393
#Part-A Aptitude & General Biotechnology
Which of the following statement(s) regarding transcription initiation and RNA Pol III is (are) true?
#Question id: 4395
#Part-A Aptitude & General Biotechnology
Which of the following chemicals would be the most appropriate for the 5’ labeling of a DNA strand with a radioactive phosphate?
#Question id: 4480
#Part-B Specialized Branches in Biotechnology
The reason for TBP’s unorthodox recognition mechanism is
#Question id: 4481
#Part-B Specialized Branches in Biotechnology
Choose correct statements about recognition mechanism of TBP ;
A. TBP causes the minor groove to be widened to an almost flat conformation
B. It also bends the DNA by an angle of ~120o
C. The interaction between TBP and DNA involves maximum number of hydrogen bonds between the protein and the edges of the base.
D. Much of the specificity is imposed by two pairs of phenylalanine side chains that intercalate between the base pairs at either end of the recognition sequence and drive the strong bend in the DNA.
#Question id: 4483
#Part-B Specialized Branches in Biotechnology
TAF42 and TAF62 from Drosophila form a structure similar to that of the