Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm? 

P. A larger E-value indicates higher sequence similarity 

Q. E-value < 10^-10 indicates sequence homology 

R. A higher BLAST score indicates higher sequence similarity 

S. E-value > 10^10 indicates sequence homology 

#Question id: 4148

#Part-A Aptitude & General Biotechnology

Which of the following is true about the sorting pathway for proteins destined for incorporation into lysosomes or the plasma membrane of eukaryotic cells?

#Question id: 4149

#Part-A Aptitude & General Biotechnology

Glycosylation of proteins inside the endoplasmic reticulum does not involve:

#Question id: 4150

#Part-A Aptitude & General Biotechnology

Posttranslational glycosylation of proteins is inhibited specifically by:

#Question id: 4151

#Part-A Aptitude & General Biotechnology

The signal sequences that direct proteins to the nucleus are:

#Question id: 4152

#Part-A Aptitude & General Biotechnology

The pathway for polypeptides exported from E. coli includes the following steps, which occur in what order for correct export?

1.  A chaperone, SecA, binds to the polypeptide.

2.  A chaperone, SecB, binds to the polypeptide.

3.  ATP is hydrolyzed by Sec A.

4.  SecA pushes 20 amino acids of the polypeptide into the translocation complex.

#Question id: 4153

#Part-A Aptitude & General Biotechnology

Ubiquitin-mediated protein degradation is a complex process, and many of the signals remain unknown.  One known signal involves recognition of amino acids in a processed protein that are either stabilizing (Ala, Gly, Met, Ser, etc.) or destabilizing (Arg, Asp, Leu, Lys, Phe, etc.), and are located at: