TLS Online TPP Program

#Question id: 12492


A young man with phenylketonuria, who was successfully treated following diagnosis on newborn screening, is planning to start a family with his healthy, unaffected, and unrelated partner, who has no family history of phenylketonuria . Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10 000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probability that his partner is a carrier is 1 in 100.
  2. The probability that the man will transmit a mutant allele to his first child is 1 in 2.
  3. The probability that his partner will transmit a mutant allele to their first child is 1 in 50.
  4. The probability that their first child will be affected is 1 in 100.
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TLS Online TPP Program

#Question id: 5700

#Part-A Aptitude & General Biotechnology

During meiosis, homologous chromosomes pair up along their lengths. The most plausible explanation for the karyotype structure shown above is that

TLS Online TPP Program

#Question id: 5701

#Part-A Aptitude & General Biotechnology

Cross-over suppressors are production of gametes having cross over products is lethal. Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 5701

#Part-B Specialized Branches in Biotechnology

Cross-over suppressors are production of gametes having cross over products is lethal. Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 5702

#Part-B Specialized Branches in Biotechnology

What is probability of couple where male is karyotypically normal and the female in pericentric inversion in heterozygous condition produced child with disability if no crossing over takes placed within pericentric inversion. (Note: Duplication and deletion in gamete will results  in disability)

TLS Online TPP Program

#Question id: 5703

#Part-B Specialized Branches in Biotechnology

Robertsonian translocation is reciprocal exchange of genetic segment between two acrocentric chromosomes. Which of the following is incorrect statement?

TLS Online TPP Program

#Question id: 5703

#Part-A Aptitude & General Biotechnology

Robertsonian translocation is reciprocal exchange of genetic segment between two acrocentric chromosomes. Which of the following is incorrect statement?