TLS Online TPP Program

#Question id: 12493


Cystic fibrosis shows autosomal recessive inheritance with an incidence of 1 in 2500. The unaffected brother of an affected girl is referred for genetic counseling. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probability that the brother is a carrier is 1/2.
  2. If the brother has a child with a healthy unrelated partner the probability that the child will be affected is 1 in 150.
  3. If the brother has a child with his first cousin the probability that the child will be affected is 1 in 12.
  4. If the affected sister has a child with her first cousin the probability that the child will be affected is 1 in 4.
More Questions
TLS Online TPP Program

#Question id: 797

#Part-B Specialized Branches in Biotechnology

With respect to microRNAs, which, if any, of the following statements, is FALSE?)

A. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

B. Like an mRNA a miRNA is initially produced as a larger precursor RNA that, like the great majority of mRNAs, usually has a 5’ cap and a poly(A) tail.

C. MicroRNAs are produced by germ-line cells only.

D. A miRNA is initially produced as a duplex RNA but in order to work it needs to be converted into a single-strand RNA.

E. MicroRNAs usually work as transcription factors.

TLS Online TPP Program

#Question id: 799

#Part-B Specialized Branches in Biotechnology

The two cleavage reactions required to generate the miRNA from these primary transcripts are mediated by two distinct RNases. A characteristic of both these enzymes is that they recognize and cleave RNAs on the basis of the structure of their substrates rather than their specific sequence. Which of the following statement is INCORRECT regarding the cleavage reactions that produces a mature RNA?

TLS Online TPP Program

#Question id: 801

#Part-B Specialized Branches in Biotechnology

Identify the type of DNA from the structures given below and match the correct form with its characteristics described.

TLS Online TPP Program

#Question id: 803

#Part-B Specialized Branches in Biotechnology

A single-stranded DNA molecule contains 40 nucleotides and has the sequence 5’-(GA)20-3’. When this single strand binds to a complementary DNA strand to form a B-DNA structure,

TLS Online TPP Program

#Question id: 810

#Part-A Aptitude & General Biotechnology

Which of the following statements concerning the process of spontaneous folding of proteins is false?

TLS Online TPP Program

#Question id: 811

#Part-A Aptitude & General Biotechnology

Protein S will fold into its native conformation only when protein Q is also present in the solution.  However, protein Q can fold into its native conformation without protein S.  Protein Q, therefore, may function as a ____________ for protein S.