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#Question id: 12491


Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

#Part-B Specialized Branches in Biotechnology
  1. The frequency of the mutant allele is 1 in 1000.
  2. The frequency of the normal (wild-type) allele is 49/50.
  3. The carrier frequency is 1 in 100.
  4. The carrier frequency is approximately 1 in 50.
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TLS Online TPP Program

#Question id: 18676

#Part-A Aptitude & General Biotechnology

which of the following technique can be analysed hybridisation probes,  gene-cloning use as primers for DNA sequencing,  the polymerase chain reaction (PCR), use in site-directed mutagenesis and use as antisense therapeutics

TLS Online TPP Program

#Question id: 18677

#Part-A Aptitude & General Biotechnology

Point mutations in DNA, such as occur in a range of human diseases, can be identified by 

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#Question id: 18678

#Part-A Aptitude & General Biotechnology

which of the following technique can be analysed of PCR products from HIV-I allowed the identification of between 200 000 and 500 000 viral particles per cubic centimetre of serum.

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#Question id: 18679

#Part-A Aptitude & General Biotechnology

Chiral compounds can be resolved using

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#Question id: 18680

#Part-A Aptitude & General Biotechnology

DNA from Salmonella species, when digested with the restriction enzyme Xba I, gives around 15 fragments ranging from 25 kb to 680 kb This pattern of fragments, or ‘fingerprint’, is unique to that strain. If the same fingerprint is found from bacteria from other infected people, then it can be assumed that they were all infected from a common source. Thus, by comparing their eating habits, food sources, etc. the source of the infection can be traced to a restaurant, food item. The fingerprints are created and analysed by

TLS Online TPP Program

#Question id: 18681

#Part-A Aptitude & General Biotechnology

Highly heterogeneous mixtures of proteins such as cell lysates or tissue extracts should be completely fractionated into individual proteins so as to obtain an overall picture of the protein composition and to enable location of individual proteins. The highest resolution is obtained