CDK activity is modulated by the following proteins:

(a) cyclin, (b) CAK, (c) Wee1,  (d) p21. Following protein act as:

I. Inhibitory kinase

II. CKI Family of proteins

III. Activatory kinase

IV. Regulatory subunit

Which of the following is correct?

#Question id: 13076

#Part-A Aptitude & General Biotechnology

Restriction fragment length polymorphism denotes that a single restriction enzyme produces fragments of different lengths from the same stretch of genomic DNA of different strains of a species or from different related species. RFLPs are detected as follows:

i.  Large molecular weight genomic DNA is isolated from several strains or related species;

ii.  The fragments in these digests are separated through electrophoresis

iii.  These 'DNAs are then digested with a selected restriction enzyme

iv.  Exposed to a suitably radio-labelled appropriate DNA probe under conditions favouring DNA: DNA hybridization

v.  The resulting gel lanes are transferred and fixed to a suitable solid support and

vi.   The free probes are removed

vii.  The fragments to which the probe has hybridized are detected by filming them as distinct bands on a suitable photofilm through autoradiography.

#Question id: 15000

#Part-B Specialized Branches in Biotechnology

#Question id: 12817

#Part-A Aptitude & General Biotechnology

#Question id: 7458

#Part-A Aptitude & General Biotechnology

#Question id: 3271

#Part-A Aptitude & General Biotechnology

Consider hemophilia A, a clotting disorder caused by an X-linked recessive allele with a frequency (q) of approximately 1 in 10,000. The frequency of the disease among females and among male respectively