Practice Questions

TLS Online TPP Program

#Question id: 12187

How cells know whether sister kinetochores are properly attached to the mitotic spindle?

#Part-B Specialized Branches in Biotechnology

When sister chromatids are correctly attached to microtubules, their kinetochores are under tension. Mitotic spindle attached to the kinetochores pull at them, and the cohesin molecules that hold the sister chromatids together withstand these forces, creating tension at kinetochores.
When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. One kinetochore attaches to microtubules emanating from two opposite spindle poles.
When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. Both sister kinetochores attach to microtubules emanating from the same spindle pole.
When sister chromatids are correctly attached to microtubules, their kinetochores are not under tension. Only one of the two sister kinetochores attaches to microtubules.