In the human disease known as lupus, there is an immune reaction against a patientʹs own DNA from broken or dying cells. This kind of response typifies which kind of irregularity?

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#Question id: 3653

#Part-A Aptitude & General Biotechnology

Cyclobutane pyrimidine dimers are formed by -------------from adjacent pyrimidines on one strand by cyclization of the double-bonded C5 and C6carbon atoms of each base to give a cyclobutane ring.

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#Question id: 3654

#Part-A Aptitude & General Biotechnology

Cleavage of the cyclobutane ring of pyrimidine dimers by ______________ restores the original DNA structure.

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#Question id: 3655

#Part-A Aptitude & General Biotechnology

The mismatched base is removed from the daughter strand of DNA by:

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#Question id: 3657

#Part-A Aptitude & General Biotechnology

Mutations in excision repair genes or a translesion DNA polymerase cause:

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#Question id: 3658

#Part-A Aptitude & General Biotechnology

In E. coli, the UvrABC endonuclease removes _____________and other bulky lesions by recognizing the distortion these produce in the double helix.

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#Question id: 3659

#Part-A Aptitude & General Biotechnology

In eukaryotes, gap filling in BER involves predominantly DNA polymerase β whereas the longer gaps generated in NER are filled by: