TLS Online TPP Program

#Question id: 72


For the reaction catalyzed by the enzyme hexokinase: Glucose + ATP → glucose 6-phosphate + ADP the equilibrium constant, Keq, is 7.8 × 102. In living E. coli cells, [ATP] = 5 mM, [ADP] = 0.5 mM, [glucose] = 2 mM, and [glucose 6-phosphate] = 1 mM. Which of the following conclusions made on the basis of the above calculations is incorrect?

#Section C (Domain-Specific Knowledge)
  1. The reaction is therefore far from equilibrium.

  2. The cellular concentrations of the products are much lower and those of the reactants are much higher.

  3. The reaction therefore tends strongly to go to the right.

  4. The cellular concentrations of the products are much higher and those of the reactants are much lower.

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TLS Online TPP Program

#Question id: 67

#Section C (Domain-Specific Knowledge)

When a region of DNA must be repaired by removing and replacing some of the nucleotides, what ensures that the new nucleotides are in the correct sequence?

TLS Online TPP Program

#Question id: 68

#Section C (Domain-Specific Knowledge)

Match the following functional groups given in column I with their respective representatives given in column II.

COLUMN I               COLUMN II

1. Anhydride               a. RCOOR

2. Ether                       b. ROCOCH3

3. Acetyl                     c. ROR

4. Amido                     d. RCOOCOR

5. Ester                        e. RCONH2

TLS Online TPP Program

#Question id: 69

#Section C (Domain-Specific Knowledge)

Which of the following is the diastereomer of the following compound?

TLS Online TPP Program

#Question id: 70

#Section C (Domain-Specific Knowledge)

The dimensions of living cells are limited, on the lower end by the minimum number of biomolecules necessary for function, and on the upper end by the rate of diffusion of solutes such as oxygen. Except for highly elongated cells, they usually have lengths and diameters in the range of

TLS Online TPP Program

#Question id: 71

#Section C (Domain-Specific Knowledge)

Which of the following is not the priority rule for R, S Configuration?

TLS Online TPP Program

#Question id: 73

#Section C (Domain-Specific Knowledge)

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

COLUMN I

COLUMN II

 

 

 

  ΔH

ΔS

ΔG = ΔH – TΔS

1.

+

a. The reaction is both enthalpically and entropically opposed. It is nonspontaneous (endergonic) at all temperatures.

2.

 −

− 

b. The reaction is enthalpically opposed (endothermic) but entropically favored. It is spontaneous only at temperatures above T = ΔH/ΔS.

3.

+

+

c. The reaction is enthalpically favored but entropically opposed. It is spontaneous only at temperatures below T = ΔH/ΔS.

4.

+

d. The reaction is both enthalpically favored (exothermic) and entropically favored. It is spontaneous (exergonic) at all temperatures.