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#Section 2: General Biology #T cells #Part B Pointers
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#Section 3: Genetics, Cellular and Molecular Biology

Two N- acetylglucosamine (GlcNAc) and five mannose residues are added one at a time to a dolichol phosphate on the cytosolic face of the ER membrane

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#Section 3: Genetics, Cellular and Molecular Biology

When E2Fs are bound to Rb, not only are they transcriptionally inactive, but they also function to repress transcription by recruiting chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines.

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#Section 3: Genetics, Cellular and Molecular Biology

Defects in LIS1 
Miller-Dieker lissencephaly
means “smooth brain”

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#Section 3: Genetics, Cellular and Molecular Biology

The ER captures selected proteins from the cytosol as they are being synthesized. These are of two types:

Transmembrane proteins

Water-soluble proteins

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#Section 3: Genetics, Cellular and Molecular Biology

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