B cells migrate to the lymphoid follicles. They are directed there by chemokine interactions between CXCL13, which is secreted by follicular dendritic cells (FDCs).

TLS Online TPP Program

#Id: 10389

#Section 2: General Biology

Class II, but not class I, presentation is inhibited by treatment of the cells with an agent that blocks endocytic processing within the cell (chloroquine).

TLS Online TPP Program

#Id: 10286

#Section 2: General Biology

T cells initiate the adaptive immune response by interacting MHC on antigen-presenting cells that have been exposed to pathogens. 

TLS Online TPP Program

#Id: 10287

#Section 2: General Biology

T-Cell - Cells leaving the thymus are functional, mature T cells expressing unique and specific T-cell receptors (TCRs) that are both tolerant to self and restricted to self-MHC.

TLS Online TPP Program

#Id: 10288

#Section 2: General Biology

TLS Online TPP Program

#Id: 10289

#Section 2: General Biology

T-cell lineage

TLS Online TPP Program

#Id: 10290

#Section 2: General Biology

T-Cell Development

1.Commitment

2.antigen receptor gene rearrangements

3.The selection and expansion of cells (β-selection