TLS Online TPP Program

#Id: 8602

#Section 3: Genetics, Cellular and Molecular Biology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8603

#Section 3: Genetics, Cellular and Molecular Biology

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28 

TLS Online TPP Program

#Id: 8604

#Section 3: Genetics, Cellular and Molecular Biology

G1/S Cyclin–CDKs

In human - cyclin E-CDK 2 

In budding yeast - CIn 1/2-Cdc 28

TLS Online TPP Program

#Id: 8605

#Section 3: Genetics, Cellular and Molecular Biology

S phase Cyclin–CDKs

In human - cyclin A-CDK 2 

In budding yeast - CIb 5/6-Cdc 28

TLS Online TPP Program

#Id: 8606

#Section 3: Genetics, Cellular and Molecular Biology

M phase Cyclin–CDKs

In human - cyclin A-CDK 1

cyclin B-CDK 1

In budding yeast - CIb 1/2/3/4-Cdc 28

TLS Online TPP Program

#Id: 8607

#Section 3: Genetics, Cellular and Molecular Biology

Cdk1 

=Cdc2 (vertebrates and fission yeast)

= Cdc28  (budding yeast)