TLS Online TPP Program

#Id: 8889

#Section 3: Genetics, Cellular and Molecular Biology

Centrosomes contain γ tubulin, which forms specific ringlike complexes (γ TuRCs) that, have the ability to nucleate microtubules and form a bipolar spindle

TLS Online TPP Program

#Id: 8890

#Section 3: Genetics, Cellular and Molecular Biology

Mitotic spindle attach to chromosomes via specialized protein structures known as kinetochores

TLS Online TPP Program

#Id: 8891

#Section 3: Genetics, Cellular and Molecular Biology

Kinetochores assemble on regions of chromosomal DNA marked by a centromere-specific H3 histone variant called CENP-A.

TLS Online TPP Program

#Id: 8892

#Section 3: Genetics, Cellular and Molecular Biology

Amphitelic attachment, 

sister kinetochores attach to microtubules emanating from opposite spindle poles, they are stably attached

TLS Online TPP Program

#Id: 8893

#Section 3: Genetics, Cellular and Molecular Biology

Merotelic attachment 

A kinetochore can attach to microtubules emanating from both poles at the same time

TLS Online TPP Program

#Id: 8894

#Section 3: Genetics, Cellular and Molecular Biology

Syntelic attachment 

Both kinetochores of a sister chromatid pair can attach to microtubules from the same pole