The efficient formation of disulfide bonds in the lumen of the ER depends on the enzyme protein disulfide isomerase (PDI), which is present in all eukaryotic cells

TLS Online TPP Program

#Id: 9212

#Section 3: Genetics, Cellular and Molecular Biology

Loss of their original diversity per generation

=1/2n

Gain of their original diversity per generation

=1/2n 

Gain or Loss of their original diversity per generation

=1/4n

TLS Online TPP Program

#Id: 9213

#Section 3: Genetics, Cellular and Molecular Biology

Probability of being heterozygote in given population

H = 1 - 1/2N

TLS Online TPP Program

#Id: 9214

#Section 3: Genetics, Cellular and Molecular Biology

Effective population size(Ne)

Effective number of breeding adults in a population.

TLS Online TPP Program

#Id: 9215

#Section 3: Genetics, Cellular and Molecular Biology

Some factor determine Ne

1.Sex ratio.

2.Variation between individual in reproduction success.

3.Fluctuation in population size.

4.The age structure of the population.

5.Mating is random.

TLS Online TPP Program

#Id: 9216

#Section 3: Genetics, Cellular and Molecular Biology

Ne = Male + Female  (when both are equal)

Ne = 4 × n(male) × n(female)/n(male)+n(female) 

(When both unequal Ne is smaller than then sum of both)

TLS Online TPP Program

#Id: 8950

#Section 3: Genetics, Cellular and Molecular Biology