Membranes of late endosomes and lysosomes contain V-class proton pumps that act in concert with Cl- channels to acidify the vesicle lumen.

TLS Online TPP Program

#Id: 10317

#Section 2: General Biology

Cytotoxic T Cells target tumor cells

Most tumor cells, express MHC class I molecules on their surface, cytotoxic T cells can directly recognize them. 

cytotoxic T cells can result in killing of the tumor cells by two different mechanisms

TLS Online TPP Program

#Id: 8154

#Section 3: Genetics, Cellular and Molecular Biology

Sar1 GTPase drives the pinching off of COPII vesicles

ARF GTPase drives the pinching off of COPIvesicles

Dynamin GTPase drives the pinching off of clathrin-coated vesicles

TLS Online TPP Program

#Id: 8370

#Section 3: Genetics, Cellular and Molecular Biology

In the absence of ATP, the myosin head is firmly attached to the actin filament. 

TLS Online TPP Program

#Id: 8619

#Section 3: Genetics, Cellular and Molecular Biology

INK4s

bind to CDK4 and CDK6 monomers, blocking their interaction with cyclin D

TLS Online TPP Program

#Id: 9155

#Section 3: Genetics, Cellular and Molecular Biology

Inbreeding coefficient (F)

Probability that an individual has two identical alleles for a given gene.

Inbreeding coefficients can range from 0 to 1.