TLS Online TPP Program

#Id: 10320

#Section 2: General Biology

The tumor cells may acquire additional oncogenic mutations that allow them to escape the immune system.

TLS Online TPP Program

#Id: 8611

#Section 3: Genetics, Cellular and Molecular Biology

Nonphosphorylated CDK bound to one of its cyclin partners has minimal but detectable protein kinase activity in vitro, although it may be essentially inactive in vivo.

TLS Online TPP Program

#Id: 10319

#Section 2: General Biology

Fas-L on the cytotoxic T cell binds to its receptor, the Fas protein on the tumor cells, an apoptotic signaling pathway in the tumor cells becomes activated, which also leads to tumor cell death. 

TLS Online TPP Program

#Id: 8607

#Section 3: Genetics, Cellular and Molecular Biology

Cdk1 

=Cdc2 (vertebrates and fission yeast)

= Cdc28  (budding yeast)

TLS Online TPP Program

#Id: 8887

#Section 3: Genetics, Cellular and Molecular Biology

The mitotic CDKs phosphorylate specific nucleoporins, which causes nuclear pore complexes to dissociate during prophase.