Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene

TLS Online TPP Program

#Id: 9297

#Section 2: General Biology

Nitrite reductase

Nitrite (NO2-) is a highly reactive, potentially toxic ion.

Plant cells immediately transport the nitrite into chloroplasts or plastids.

The enzyme nitrite reductase reduces nitrite to ammonium.

Leaf chloroplasts and root plastids contain different forms of nitrite reductase.

Each polypeptide contains two prosthetic groups, an iron-sulfur group and a specialized heme.

NO3-, high sucrose conc, and light induce the transcription of nitrite reductase mRNA.

Asparagine and glutamine repress the induction.

TLS Online TPP Program

#Id: 8878

#Section 3: Genetics, Cellular and Molecular Biology

At the same time that Cdc25C is being activated, mitotic CDKs and Plk1 phosphorylate Wee1, which targets it for destruction through a phosphobinding SCF protein-ubiquitin ligase. This forms positive feedback loop 2

TLS Online TPP Program

#Id: 8034

#Section 2: General Biology

Nonpolar amino acids have three ionisations zones

1. 1--------pK1 – charge +1

2. pK1---------pK2 charge 0

3. pK2---------14 charge -1

TLS Online TPP Program

#Id: 9266

#Section 2: General Biology

N2 constitutes about 80% of the earth’s atmosphere, but the stability of its triple bond renders it inert and metabolically inaccessible to most organisms.

TLS Online TPP Program

#Id: 9277

#Section 2: General Biology

Nod factor is b-1,4-linked N-acetyl-D-glucosamine backbone