At the metaphase to anaphase transition, APC/C bound to Cdc20 targets cyclins A /B and securin for degradation.

TLS Online TPP Program

#Id: 7955

#Section 3: Genetics, Cellular and Molecular Biology

Only asparagine residues in the tripeptide sequences Asn-X-Ser and Asn-X-Thr (where X is any amino acid except proline) are substrates for oligosaccharyl transferase.

TLS Online TPP Program

#Id: 7943

#Section 3: Genetics, Cellular and Molecular Biology

Classes of ER membrane proteins

TLS Online TPP Program

#Id: 10368

#Section 2: General Biology

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.

TLS Online TPP Program

#Id: 7944

#Section 3: Genetics, Cellular and Molecular Biology

Membrane and soluble secretory proteins synthesized on the rough ER undergo four principal modifications before they reach their final destinations: 

(1) Glycosylation in the ER and Golgi complex

(2) Formation of disulfide bonds in the ER

(3) Proper folding of polypeptide chains and assembly of multisubunit proteins in the ER

(4) Specific proteolytic cleavages in the ER, Golgi complex, and secretory vesicles

TLS Online TPP Program

#Id: 7763

#Section 2: General Biology

Breaking a bond always require energy to be added to the molecule. Correspondingly, making a bond always releases energy.