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Phosphorylation on multiple sites by G1 CDKs blocks Rb from associating with E2F and promotes its export out of the nucleus.

#Section 3: Genetics, Cellular and Molecular Biology #CELL CYCLE #Part B Pointers
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#Section 2: General Biology

The number of neutrons is equal to the difference between the mass number of the atom (M) and the atomic number (Z).

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#Id: 9167

#Section 3: Genetics, Cellular and Molecular Biology

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#Section 2: General Biology

Expression of class II molecules by B cells is down-regulated by IFN-Â¥.

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#Section 2: General Biology

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#Id: 10384

#Section 2: General Biology

Class II MHC transcriptional activator called CIITA and another transcription factor called RFX, have both been shown to activate the promoter of class II MHC genes.
Defects in these transcription factors cause one form of bare lymphocyte syndrome.

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