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Most protein-encoding genes, the synonymous rate of change is considerably higher than the nonsynonymous rate because synonymous mutations are tolerated by natural selection

#Section 3: Genetics, Cellular and Molecular Biology #Concepts Of Neutral Evolution #Part B Pointers
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TLS Online TPP Program

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#Section 3: Genetics, Cellular and Molecular Biology

TLS Online TPP Program

#Id: 8172

#Section 3: Genetics, Cellular and Molecular Biology

Effector proteins of Rab6 is Kinesin
Effector proteins of Rab27 is Type V Myosin

TLS Online TPP Program

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#Section 3: Genetics, Cellular and Molecular Biology

In mammalian cells, Rab5 protein (early endosomes) and its effector protein known as EEA1 (early endosome antigen 1)

TLS Online TPP Program

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#Section 3: Genetics, Cellular and Molecular Biology

In yeast Rab protein is the Sec4 and its effectors are exocyst and Type V Myosin.

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#Section 3: Genetics, Cellular and Molecular Biology

Rab·GTP is enabled to bind to a variety of different proteins, known as Rab effectors.


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#Section 3: Genetics, Cellular and Molecular Biology

Rab GTPases 
associate with transport vesicles and act as key regulators of vesicle trafficking to and fusion with the appropriate target membrane.

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